激素受体状态
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为何检测?
何时检测?
当医生需要判断乳腺癌的发展是否受雌激素和/或孕酮激素影响时,可进行此项检测。
何种样本?
活组织检查采集的乳房肿瘤组织,或在乳房肿瘤切除术手术、乳房切除术时切除的肿瘤组织。
检测样本
检测什么?
雌激素受体(ER)和孕酮受体(PR)为机体某些细胞的特异性蛋白质。这些受体可与雌激素和孕酮(血液中的女性激素)结合,可促进细胞的生长和分化。
许多乳腺癌肿瘤通常具有大量的雌激素或孕酮受体(称为激素依赖型肿瘤),雌激素和/或孕酮可促进其生长。通过检测激素受体水平可了解乳房肿瘤组织是否具有这些受体。
测试样本如何采集?
试验
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参考文献
注意:本文是在此处引用的参考文献和医学检验项目在线介绍编辑审核委员会全体成员的经验和研究结果的基础上总结而成。本文由编辑委员会定期审核、更新。任何新引用的文献都会添加到列表中,并且会与原有的参考文献区分开。
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NCI (1999 October, last update). PDQ Treatment Summary for Health Professionals: Breast Cancer [35 paragraphs] The National Cancer Institute of The National Institutes of Health [On-line information]. Available FTP: http://my.webmd.com/content/article/1680.50695
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