表皮生长因子受体
您是否在找估计的肾小球滤过率，也称为eGFR？
快速浏览
为何检测？
检测是否存在实体肿瘤，如在肺癌（非小细胞）、头颈部肿瘤、结肠癌、胰腺癌或乳腺癌中，表皮生长因子受体检测是阳性的，并可用于指导治疗并判断预后。
何时检测？
当您被诊断患有某些侵袭性肿瘤，您的医生希望知道表皮生长因子受体是否在肿瘤中过度表达时。
何种样本？
通过活检获得的肿瘤组织样本。
是否需要作试验前准备？
不需要。
检测样本
检测什么？
表皮生长因子受体是细胞膜受体家族的成员，有助于调节细胞生长、分裂、生存和死亡。在多种肿瘤中其表达量增加，这可能是由于受体扩增及过度表达，导致生长信号过强。表皮生长因子受体蛋白增加，使肿瘤更具侵袭性、更可能转移、并对标准化疗更不敏感，具有这些肿瘤的患者往往预后不佳。因此，针对表皮生长因子受体的肿瘤治疗是一种有价值的的分子治疗方法。表皮生长因子受体特异性抗体与受体结合可阻断生长信号，被用于治疗某些恶性肿瘤。
检测肿瘤内扩增或过表达的表皮生长因子受体有两种主要的方式：一种方法是检测表皮生长因子受体蛋白质的含量；另一种方法是在基因水平检测基因扩增——用以评价基因的拷贝数。
测试样本如何采集？
通过活检获得肿瘤组织样本。活检程序由受累器官决定。
是否需要进行任何试验前准备以保证样本的质量？
不需要任何试验前准备。
试验
常见问题
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参考文献
注意：本文是在此处引用的参考文献和医学检验项目在线介绍编辑审核委员会全体成员的经验和研究结果的基础上总结而成。本文由编辑委员会定期审核、更新。任何新引用的文献都会添加到列表中，并且会与原有的参考文献区分开。
Sources Used in Most Recent Review
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Sources Used in Previous Reviews
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