CA19-9
快速浏览
为何检测？
鉴别胰腺癌与胆管癌以及其他状况；监测胰腺癌的治疗以及复发。
何时检测？
医生怀疑发生胰腺癌以及胰腺癌的治疗中和治疗后。
何种样本？
采自肘静脉的血液样本。
是否需要作试验前准备？
不需要。
检测样本
检测什么？
CA19-9是出现在一些细胞表面的蛋白质。CA19-9并不引起癌症发生，而是肿瘤细胞脱落的蛋白。它作为肿瘤标记物来监测癌症进程是非常有用的。
大多数进展期的胰腺癌患者会发生CA19-9的升高，但是在其他一些情况下也会升高，例如：结肠癌、肺癌、胆囊癌、胆结石、胰腺炎、囊性纤维化和肝病。发生胆管阻塞时，CA19-9水平急剧升高，当阻塞清除时就会下降。所以当发生胆管阻塞前检测CA19-9，在治疗阻塞一到二周后，重复检测CA19-9，可以鉴别CA19-9升高是胆管阻塞本身引起的，还是癌症引起的。在健康人群中也可能有微量CA19-9。
测试样本如何采集？
自肘静脉采集血液样本。
是否需要进行任何试验前准备以保证样本的质量？
不需要。
试验
常见问题
询问检验医学专家
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参考文献
注意：本文是在此处引用的参考文献和医学检验项目在线介绍编辑审核委员会全体成员的经验和研究结果的基础上总结而成。本文由编辑委员会定期审核、更新。任何新引用的文献都会添加到列表中，并且会与原有的参考文献区分开。
Sources Used in Current Review
Pagana, K. D. & Pagana, T. J. (© 2007). Mosby's Diagnostic and Laboratory Test Reference 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 216-217.
Clarke, W. and Dufour, D. R., Editors (© 2006). Contemporary Practice in Clinical Chemistry: AACC Press, Washington, DC. Pp 246.
(Revised 2008 December 08). Tumor Markers. American Cancer Society [On-line information]. Available online at http://www.cancer.org/docroot/PED/content/PED_2_3X_Tumor_Markers.asp?sitearea=PED through http://www.cancer.org. Accessed August 2009.
(Updated 2009 May) Tumor Markers. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/resources/print/TumorMarkers.pdf through http://www.arupconsult.com. Accessed August 2009.
Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Burtis CA, Ashwood ER and Bruns DE, eds. 4th ed. St. Louis, Missouri: Elsevier Saunders; 2006 Pp 773.
Sources Used in Previous Reviews
Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].
Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby's Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO.
ACS. All About Pancreatic Cancer, Pancreatic Cancer Detailed Guide. American Cancer Society.
ASCO (1996 May 17, adopted, revision every 3 years). CA 19-9 as a Marker for Colon Cancer. American Society for Clinical Oncologists, Clinical Practice Guidelines for the Use of Tumor Markers in Breast and Colorectal Cancer [On-line guidelines]. Available online at http://www.asco.org/prof/pp/html/guide/tumor/m_tumor6.htm through http://www.asco.org.
NCI (2002, February 8, posted). What you Need to Know about Cancer of the Pancreas. National Cancer Institute, cancer.gov [On-line information]. Available online through http://www.cancer.gov.
Reid, C. (1996 October). Probing the Pancreas. U.S. Food and Drug Administration [On-line article]. Available online at http://vm.cfsan.fda.gov/~dms/fdpancre.html through http://vm.cfsan.fda.gov.
Mayer, R. (1999 - 2002 copyright). Pancreatic Cancer. The National Pancreas Foundation [On-line article]. Available online at http://www.pancreasfoundation.org/pancreaticcancerarticle.html through http://www.pancreasfoundation.org.
Check, W. (1998 July) Reaching agreement on tumor markers. CAP Today, In the News [On-line journal]. Available online at http://www.cap.org/captoday/archive/1998/julycover.html through http://www.cap.org.
NCI (1998 April 27). Tumor markers. National Cancer Institute, Cancer Facts [On-line information]. Available online at http://cis.nci.nih.gov/fact/5_18.htm through http://cis.nci.nih.gov.
ACS (2000 July 19). Tumor Markers. American Cancer Society, Prevention and Early Detection [On-line information]. Available online through http://www.cancer.org.
