抗核抗体
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为何检测？
用于筛查某些自身免疫性疾病，如系统性红斑狼疮（SLE）、多发性肌炎等。
何时检测？
当您的医生认为患者具有自身免疫性疾病症状时。
何种样本？
采自肘静脉的血液样本。
是否需要作试验前准备？
不需要；然而一些药物会干扰该试验，请告诉您的医生你正在服用的任何药物。.
检测样本
检测什么？
该试验检测的是血液中是否有ANA。当机体无法充分识别“自我”与“非我”时，免疫系统会产生一组特别的抗体，即ANA，这些自身抗体攻击机体细胞引起相应症状、体征如组织器官感染、关节肌肉疼痛、易疲劳。ANA是自身免疫的标志，并且与多种自身免疫性疾病相关，但最常见于系统性红斑狼疮（SLE）。
测试样本如何采集？
该试验检测的是血液中是否有ANA。当机体无法充分识别“自我”与“非我”时，免疫系统会产生一组特别的抗体，即ANA，这些自身抗体攻击机体细胞引起相应症状、体征如组织器官感染、关节肌肉疼痛、易疲劳。ANA是自身免疫的标志，并且与多种自身免疫性疾病相关，但最常见于系统性红斑狼疮（SLE）。
是否需要进行任何试验前准备以保证样本的质量？
没有。但是某些药物会干扰试验，因此应将所服药物情况告诉您的医生。
试验
常见问题
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参考文献
注意：本文是在此处引用的参考文献和医学检验项目在线介绍编辑审核委员会全体成员的经验和研究结果的基础上总结而成。本文由编辑委员会定期审核、更新。任何新引用的文献都会添加到列表中，并且会与原有的参考文献区分开。
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Steven Lobel, PhD, D-ABMLI, MBA. Laboratory Director, Quest Diagnostics, Baltimore, MD.
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H. James Williams, MD. Professor of Medicine, Thomas E. and Rebecca D. Jeremy Presidential Endowed Chair for Arthritis Research, University of Utah School of Medicine, Salt Lake City, UT.
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Pagana, Kathleen D. & Pagana, Timothy J. (© 2007). Mosbys Diagnostic and Laboratory Test Reference 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 90-92.
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Reeves, W. (2006 July). Fluorescent Antinuclear Antibody (FANA) Test: False Positive [23 paragraphs]. American College of Rheumatology [On-line information]. Accessed on: 4/9/07 Available FTP: http://www.rheumatology.org/public/factsheets/fana.asp
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Relchlin, M. (2005 February 3, Updated). Laboratory Tests Used in the Diagnosis of Lupus [24 paragraphs]. Lupus Foundation of America [On-line information]. Accessed on: Available FTP: http://www.lupus.org/education/brochures/labtests.html
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(2003 August, Revised). Systemic Lupus Erythematosus [4 pages of 40]. National Institute of Arthritis and Musculoskeletal and Skin Diseases, Handout on Health [On-line information]. Accessed on: 4/15/07 Available FTP: http://www.niams.nih.gov/hi/topics/lupus/slehandout/
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Peter JB:Antinuclear antibodies, in Use and Interpretation of Laboratory Tests in Rheumatiology, James B Peter, ed. Speciality Laboratories: Los Angeles. pp 10-11, 1998.
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Pagana, Kathleen D. & Pagana, Timothy J. (2006). Mosbys Manual of Diagnostic and Laboratory Tests 3rd Edition: Mosby Elsevier, Saint Louis, MO. Pp 91-93.
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Burtis C, Ashwood E, Bruns D, eds. (2006) Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 4th edition, Saunders, Elsevier.
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Arbuckle MR et al. Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med 2003 Oct 16; 349:1526-33.
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